95% of vaccinated Rhesus monkeys survived lethal doses of inhaled anthrax.

US Army Medical Research Institute of Infectious Diseases performed these studies between 1990 and 2001.

These data resulted from various vaccine doses and lengths of time between vaccination and lethal challenge.


62 of 65 vaccinated monkeys (95%) survived lethal inhalational challenge,
but 0 of 18 unvaccinated monkeys (0%) survived.

The test doses were hundreds to thousands of times the average lethal dose.

97% of vaccinated rabbits survived lethal doses of inhalational anthrax.

US Army Medical Research Institute of Infectious Diseases performed these studies between 1990 and 2001.


114 of 117 vaccinated rabbits (97%) survived lethal inhalational challenge,
but 0 of 28 unvaccinated rabbits (0%) survived.

These data resulted from various vaccine doses and lengths of time between vaccination and lethal challenge.

Vaccines protected guinea pigs from inhaled anthrax modestly, about 22%.

This is probably because guinea pig lungs differ from human lungs.

Because of the lung differences, guinea pigs are not as good a model of inhaled anthrax as monkeys and rabbits.